BCG vaccine research. Technician in gloves and mask inserts cell lines into a cylinder of liquid nitrogen. The cells are for research into a DNA BCG (bacille Calmette-Guerin) vaccine against TB (tuberculosis). A DNA vaccine consists of purified DNA that codes for a disease antigen. Professor Content and Dr Huygen at the Brussels Pasteur Institute have developed a vaccine that codes for antigen 85 extracted from BCG. Here, cell lines stored at -195 degrees Celsius can be thawed, cultured & used in research when needed. A DNA BCG vaccine could be very important in the global fight against TB. Unlike traditional BCG vaccine, a DNA vaccine could also protect people with HIV.