Diabetic retinopathy: fundus camera image of the retina of the eye in a case of severe diabetic retinopathy, the damage to the blood supply of the retina that occurs as a complication of diabetes. Diabetic retinopathy is the result of blockages in capillaries and small arteries (arterioles) with a resulting reduction in or cessation of blood flow (non-perfusion) to some areas of the retina. Also, an increase in the permeability of blood vessels underlies the formation of haemorrhages, fatty exudates (yellow areas) and oedema (fluid accumulation). Diabetic retinopathy is a major cause of blindness.