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Coagulation factor complex molecule
Coagulation factor complex molecule. Molecular model showing the interaction between coagulation factor VIII (FVIII, pink, blue and yellow), factor IXa (FIXa, cream and grey) and the phospholipid membrane (yellow and grey) of a blood platelet. The secondary structures (ribbons) of the molecules are shown, with the primary structure (atoms, spheres) of the active site of the factor IXa enzyme shown. These proteins are involved in the coagulation cascade, the physiological process that leads to blood clotting in the case of an injury. This complex of FVIII and FIXa activates factor X in both the extrinsic and intrinsic activation pathways.
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