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Oestrogen receptor complex
Oestrogen receptor complexed with the female sex hormone estradiol. Computer model showing a human oestrogen receptor (green, blue-green) complexed with estradiol (grey, red). The front part of the molecule has been removed in order to show the complexed estradiol. Oestradiol is one of three naturally-occurring oestrogens. Oestrogen receptors are cytoplasmic proteins that bind oestrogens and then migrate to the nucleus where they can regulate DNA transcription.
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