RM
Enzyme catalysing DNA recombination
Enzyme catalysing DNA recombination. Molecular model of the enzyme flippase recombinase (FLP recombinase, red and yellow) mediating the recombination of strands of DNA (deoxyribonucleic acid, green) at a Holliday Junction. Two views (main image at left, image at right rotated sideways) of this process are shown. This recombination is a natural genetic process known as crossing over, and involves the mixing of two strands of DNA. Recombinase enzymes snip open each DNA strand, starting the process going and forming a four-way alignment known as a Holliday Junction (seen in the foreground image at left). This enzyme is derived from Saccharomyces cerevisiae (Baker's yeast). It is acting as both a ligase (bond-forming enzyme) and a lyase (bond-breaking enzyme).
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