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Neurons in Tay-Sachs disease, illustration
Neurons in Tay-Sachs disease. Illustration showing swollen neurons with membraneous lamellar inclusions due to accumulation of gangliosides in lysosomes, myelin degradation. Tay-Sachs disease is a disorder that progressively destroys brain neurons, is caused by a mutation in the HEXA gene of chromosome 15 leading to deficiency of hexosaminidase A. Tay-sachs is most commonly seen in infants, manifesting in muscle weakness and decreased motor function, vision and hearing loss, and intellectual disability., by KATERYNA KON/SCIENCE PHOTO LIBRARY
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0.3 MB
724 x 407 px
6.1 x 3.4 cm
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2.8 MB
2290 x 1288 px
19.4 x 10.9 cm
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27.8 MB
7200 x 4050 px
61 x 34.3 cm
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