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Tay-Sachs disease, computer illustration
Tay-Sachs disease. Computer illustration showing a child with macrocephaly, and a close-up view of swollen neurons with lamellar inclusions due to accumulation of gangliosides. Tay-Sachs disease is a lysosomal storage genetic disorder that progressively destroys brain neurons. It is caused by a mutation in the HEXA gene of chromosome 15 leading to deficiency of hexosaminidase A. Tay-sachs is most commonly seen in infants, manifesting in muscle weakness and decreased motor function, vision and hearing loss, and intellectual disability., Photo by KATERYNA KON/SCIENCE PHOTO LIBRARY
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0.3 MB
724 x 503 px
6.1 x 4.3 cm
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3.5 MB
2290 x 1591 px
19.4 x 13.5 cm
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33.4 MB
7098 x 4930 px
60.1 x 41.7 cm
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