Illustration of an AMPA receptor (a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor). These receptors belong to the glutamate receptors and are the most common neurotransmitter receptors in the central nervous system. The upper part of the receptor is located extracellularly and recognizes and binds glutamate. The lower part is located in the membrane and, after binding glutamate, forms a channel through which ions pass across the membrane - This illustration is based on structural data from Sobolevsky, A.I., Rosconi, M.P., Gouaux, E., by medicalgraphics/F1online

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