RF
RAGE receptor, illustration
Illustration of a receptor for advanced glycation endproducts (RAGE) embedded in a cell membrane. This transmembrane protein belongs to the immunoglobulin superfamily and is able to bind to multiple molecules. Binding results in a signal cascade that causes pro-inflammatory gene activation. The expression of RAGE is stimulated by cellular stresses, such as inflammation, and so this leads to a positive feedback cycle that results in chronic inflammation. RAGE is involved in the pathogenesis of a number of diseases including diabetes, Alzheimer's disease and cancers., by JUAN GAERTNER/SCIENCE PHOTO LIBRARY
S
0.4 MB
724 x 543 px
6.1 x 4.6 cm
$ 100.00
M
3.8 MB
2290 x 1718 px
19.4 x 14.5 cm
$ 180.00
L
45.8 MB
8000 x 6000 px
67.7 x 50.8 cm
$ 350.00
More
Top Categories