Targeted protein degrader structure, illustration
Illustration of the structure of a targeted protein degrader molecule, such as a proteolysis-targeting chimera (PROTAC). Targeted protein degraders are small molecules consisting of two ligands (yellow and cyan) joined by a linker (purple). One ligand recruits a protein of interest, while the other recruits a protein ligase molecule, which leads to the ubiquitylation and subsequent degradation of the protein of interest., by THOM LEACH / SCIENCE PHOTO LIBRARY
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