Self-amplifying mRNA vaccine, illustration
Illustration of the self-amplifying mRNA (messenger ribonucleic acid) vaccine entering an antigen presenting cell/dendritic cell (orange). The self-amplifying mRNA encodes a replicase, and leads to replications of the RNA strand in the cell, which in turns leads to enhanced antigen protein translation, and a lower dose of the mRNA vaccine can be used compared with conventional mRNA vaccines. For a labelled version of this image see F042/5639., by NANOCLUSTERING/SCIENCE PHOTO LIBRARY
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